Page 9 - Journal of Structural Heart Disease Volume 1, Issue 4

Meeting Abstracts 154
to total intravenous anaesthesia (TIVA) with propofol, 2) reduced the inhaled oxygen fraction to 21%, and 3) initiated a continuous intrave- nous infusion of Prostaglandin E1 (PGE1).
Results: Complete relaxation was attained after intravenous Prosta- glandin E1 infusions of only 10-15 minutes duration. Whilst maintain- ing this protocol, 6 PDAs were successfully occluded.
Conclusion: Ductal spasm during transcatheter occlusion may be reliably resolved and the procedure safely completed by this simple protocol.
TRANSCATHETER CLOSURE OF ATRIAL SEPTAL DE- FECT PRESERVES RIGHT VENTRICULAR FUNCTION Shaimaa A. Mostafa (MD)1, Abdrabu Abdelhakim (msc)2, Tarek H. Aboelazm (MD)1, Osama S. Arafa (MD)1, Ahmed M. Elemam(MD)2
1Benha Faculty of Medicine, Egypt 2 National Heart Institute, Egypt
Aim: To investigate the intermediate and short-term e ects of tran- scatheter secundum atrial septal defect (ASD) closure on cardiac re- modeling in children and adult patients.
Methods: 50 patients with secundum ASD, referred for possible tran- scatheter device closure, were subjected to history taking, physical examination, electrocardiographic assessment and transthoracic echocardiographic examination and were evaluated before the ASD closure, and 1 day, 3 months and 6 months after closure.
Results: At the 6 months follow up, electrocardiographic parameters of remodeling improved, and P dispersion decreased from 49.73 ± 9.01 ms to 30.53 ± 5.08 ms (p = 0.004), QT dispersion decreased from 67.6 ± 5.31 ms to 51.13 ± 5.73 ms (p = 0.003), QRS duration decreased from 134.4 ± 4.97 ms to 116.20 ± 3.47 ms (P = 0.002) , PR interval de- creased from 188.87 ± 6.06 ms to 168.00 ± 6.16 ms (P = 0.002). At fol- low-up of 6 months, RVEDD had decreased from 25.67 ± 5.50 mm to 17.80 ± 2.7 mm (p = 0.001), and the LVEDD had increased from 33.17 ± 6.44 mm to 37.53 ± 5.15 mm (p = 0.002), Mean PAP decreased from 16.97 ± 3.37 mm Hg to 9.22 ± 1.37 mmHg (P = 0.000), RVSP decreased from 30.77 ± 4.69 mmHg to 18.8 ± 2.11 mmHg. After 6 months, 93.3% of the patients had normal RV size.
Conclusion: Transcatheter ASD device closure leads to signi cant im- provement in right sided chamber dimension and function and can reverse electrical and mechanical changes in atrial and ventricular myocardium in children and adults in short and intermedi- ate term follow up.
Journal of Structural Heart Disease, December 2015
Volume 1, Issue 4: 152-154