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Original Research Article
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at elevations below 8200 ft, the e ect of Denver’s ele- vation (i.e., the elevation at which the majority of our moderate altitude patients were living) may be less signi cant than expected. Still, we feel that reporting these results is important for centers at moderate el- evation.
In conclusion, patients with ASDs living at moder- ate altitude (4500–6000 ft or 1372–1829 m) were more likely to have PH or a mPAp ≥ 25 mmHg than those living at low altitude, but there was no di erence be- tween groups in Qp:Qs or clinically relevant PVR (> 3 Wood-units × m2). That is, while living at moderate altitude can raise pulmonary pressures, even when controlling for age, this did not appear to contribute to the development of PAH in our cohort of patients with ASDs.
Acknowledgements
We thank Abbie Hageman, Leda Kloudas, and Vi- jayapraveena Paruchuri for data collection. We also would like to thank Amber Khanna for her assistance with manuscript editing.
Con ict of Interest
The authors have no con ict of interest relevant to this publication.
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Journal of Structural Heart Disease, August 2017
Volume 3, Issue 4:102-106
Cite this article as: Nicolarsen J, Oestreich B, Patel SS, Aboulhosn J, Franklin WJ, Kay J. Moderate Altitude Is Not Associated with Pulmonary Arterial Hypertension in Adult Patients Referred for Transcatheter Device Closure of Atrial Septal Defects. Structural Heart Disease. 2017;3(4):102-106. DOI: https:// doi.org/10.12945/j.jshd.2017.003.17