Page 24 - Journal of Structural Heart Disease Volume 4, Issue 1

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Original Scienti c Article
that early treatment of ischemic stroke results in bet- ter patient outcomes [37], it might be worthwhile to consider post-procedure treatment plans speci cally designed for patients determined to be at a higher risk of post-procedure stroke.
Some limitations of this study must be considered. This study is a retrospective analysis of a relatively small number of patients. Although this is a multi-cen- ter study, carotid compression was performed at only one of the three study sites, and the overall number of outcome events was small. The study did not in- volve neuroimaging testing to verify the impact of carotid compression on the burden of clinically silent emboli. Larger cohort trials are needed to validate the results of this study.
In conclusion, stroke prevention by means of the non-invasive technique of using carotid compression during TAVR may not impact the incidence of TIA or disabling stroke after TAVR. Further research into the
relationship between carotid disease and post-proce- dure stroke in TAVR patients is warranted.
Acknowledgements
This investigation was supported by the Univer- sity of Utah Study Design and Biostatistics Center, with funding in part from the National Center for Research Resources and the National Center for Ad- vancing Translational Sciences, National Institutes of Health, through Grant 8UL1TR000105 (formerly UL- 1RR025764).
Con ict of Interest
The authors have no con ict of interest relevant to this publication.
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Stroke Prevention with Carotid Compression During TAVR