Page 16 - Journal of Structural Heart Disease Volume 4, Issue 2

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Original Scienti c Article
Table 3. Pre-procedural characteristics.
Delivery approach
Retrograde trans-femoral Axillary Subclavian Trans-apical Direct aortic
Table 3 (cont.). Pre-procedural characteristics.
Post procedure aortic regurgitation by uroscopy
Vascular closure technique
Characteristics
TAVI N=384
Characteristics
TAVI N=384
Delivery sheath size
Valve manufacturer
Valve Size (mm)
BAV prior to TAVI insertion BAV sizes (mm)
0.5 (2/384) 97.4 (374/384) 0.5 (2/384)
87.7 (336/383) 7.3 (28/383) 5.0 (19/383)
23mm 26mm 29mm 31mm
Yes No
18
20
22
25
26
28
Surgical closure Pre-closure percutaneous device closure Manuel pressure Surgical closure and pre-closure percuta-
neous device closure
Median total volume of contrast administered (IQR) mls
90.7 (348/384) 0.5 (2/384) 4.9 (19/384) 1.3 (5/384) 2.3 (9/384)
16g
18g >20g
Medtronic CoreValve Edwards Sapien St Jude Portico
(None) Mild) II (Moderate) III (Severe)
Peri-procedural imaging - (%) no./total no.
Contrast Aortography Additional TTE Additional TOE No additional imaging
Post procedure aortic regurgitation by TTE
0 (None) I Mild) II (Moderate)
III (Severe)
8.8 (34/384) 21.3 (82/384) 36.7 (141/384) 14.3 (55/384) 2.1 (8/384) 0.8 (3/384)
100 (383/383) 85.6 (328/383) 3.4 (13/383) 11.6 (42/383)
36.2 (138) 52.2 (199/381) 10 (38/381) 0.5 (2/381)
0 I
37.3 (140//381 45.6 (171/381 12 (45/381 0.8 (3/381
12.8 (49/384) 80.0 (307/384) 5.2 (20/384) 1.3 (5/384)
180 (20-400)
6.8 (26/384) 45.8 (176/384 40.4 (155/384) 4.9 (19/384)
85.2 (327/384) 14.6 (56/384)
TTE = transthoracic echocardiogram; TOE = transoesophageal echocardiogram
ned major and minor bleeding was seen in 3.7% and 5.8% of patients, respectively.
A few (3.4%) patients had a pre-existing perma- nent pacemaker. Some (6.0%) underwent pre-proce- dure pacing due to known right bundle branch block (overall rate 20.3%), and 14.3% required post-proce- dure in-hospital permanent pacing.
30-Day and 1-Year Mortality
Mortality at 30 days was 9.3%. Mortality at 1 year was 15.2% (n = 45/296). A Kaplan-Meier survival curve for the entire patient cohort is shown in Figure 1.
Discussion
This study reports a large consecutive and all-in- clusive historical series of patients who underwent TAVI with rst-generation self-expanding devices. This series is unique in that it captures every TAVI case performed at two high-volume centers that system- atically used a minimalist approach before MSCT be- came the imaging gold standard. It includes the en- tire “learning curve” and early experience from these centers, with robust short and long-term follow-up achieved in 100% of patients.
Cockburn J. et al.
Towards Primary TAVI