Case Reports
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Journal of Structural Heart Disease, December 2017, Volume 3, Issue 6:187-191
DOI: 10.12945/j.jshd.2017.022.17
Improvement in Pulmonary Function After Closure of Atrial Septal Defect in a Patient With Cystic Fibrosis
Abdulfattah Saidi, MD1, Holly Carveth, MD2, Anwar Tandar, MD1
1 Division of Cardiovascular Medicine, University of Utah Hospital, Salt Lake City, Utah, USA
2 Division of Pulmonary Medicine, University of Utah Hospital, Salt Lake City, Utah, USA
Abstract
Atrial septal defect (ASD) is a major cause of left-to-right intracardiac shunting. If persisting into adulthood, an ASD can lead to a larger shunt, which may eventually cause pulmonary hypertension and right ventricular failure. Large intracardiac shunts cannot be tolerated in patients with underlying lung disease such as cystic fibrosis. Although the association between an intracardiac shunt and cystic fibrosis has been reported in the literature, the impact of ASD closure on the clinical course of patients with cystic fibrosis has not been studied. Here, we report a case of ASD closure in a patient with cystic fibrosis with hypoxemia out of proportion to his lung disease. Closure of the ASD shunt resulted in significant improvement of his symptoms and pulmonary function testing.
Cite this article as: Saidi A, Carveth H, Tandar A. Improvement in Pulmonary Function After Closure of Atrial Septal Defect in a Patient With Cystic Fibrosis. Structural Heart Disease 2017;3(6):187-191. DOI: 10.12945/j.jshd.2017.022.17
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Case Reports
Journal of Structural Heart Disease, December 2017, Volume 3, Issue 6:187-191
DOI: 10.12945/j.jshd.2017.022.17
Improvement in Pulmonary Function After Closure of Atrial Septal Defect in a Patient With Cystic Fibrosis
Abdulfattah Saidi, MD1, Holly Carveth, MD2, Anwar Tandar, MD1
1 Division of Cardiovascular Medicine, University of Utah Hospital, Salt Lake City, Utah, USA
2 Division of Pulmonary Medicine, University of Utah Hospital, Salt Lake City, Utah, USA
Abstract
Atrial septal defect (ASD) is a major cause of left-to-right intracardiac shunting. If persisting into adulthood, an ASD can lead to a larger shunt, which may eventually cause pulmonary hypertension and right ventricular failure. Large intracardiac shunts cannot be tolerated in patients with underlying lung disease such as cystic fibrosis. Although the association between an intracardiac shunt and cystic fibrosis has been reported in the literature, the impact of ASD closure on the clinical course of patients with cystic fibrosis has not been studied. Here, we report a case of ASD closure in a patient with cystic fibrosis with hypoxemia out of proportion to his lung disease. Closure of the ASD shunt resulted in significant improvement of his symptoms and pulmonary function testing.
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Cite this article as: Saidi A, Carveth H, Tandar A. Improvement in Pulmonary Function After Closure of Atrial Septal Defect in a Patient With Cystic Fibrosis. Structural Heart Disease 2017;3(6):187-191. DOI: 10.12945/j.jshd.2017.022.17
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