Original Scientific Articles
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Journal of Structural Heart Disease, September 2015, Volume 1, Issue 3:127-136
DOI: 10.12945/j.jshd.2015.018-14
An Overview of the Mitraclip Procedure: Indications, Procedural Characteristics, and Clinical Outcomes
Rahul P. Sharma, MD, Moody Makar, MD, Saibal Kar, MD
Cedars Sinai Heart Institute, Los Angeles, California, USA
Abstract
The MitraClip procedure is a safe and effective approach to reduction of mitral regurgitation (MR) with proven durability and clinical improvement. Procedural success is dependent on patient selection, understanding of mitral valve anatomy, particularly from an echocardiographic perspective, and attention to critical elements of the implantation such as trans septal puncture.
In the United States, the FDA has approved the MitraClip device for treatment of high risk patients with primary MR. The question of long term, sustained reduction of MR and persistent clinical improvement remains to be addressed with longer duration of follow up. Based on the impeccable safety profile of the procedure and demonstrated medium term clinical durability, future studies should be aimed at the evaluation of MitraClip for treatment of patients with severe MR deemed moderate, or indeed low risk, for surgery.
Cite this article as: Sharma RP, Makar M, Kar S. An Overview of the Mitraclip Procedure: Indications, Procedural Characteristics, and Clinical Outcomes. Structural Heart Disease 2015;1(3):127-136. DOI: 10.12945/j.jshd.2015.018-14
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Original Scientific Articles
Journal of Structural Heart Disease, September 2015, Volume 1, Issue 3:127-136
DOI: 10.12945/j.jshd.2015.018-14
An Overview of the Mitraclip Procedure: Indications, Procedural Characteristics, and Clinical Outcomes
Rahul P. Sharma, MD, Moody Makar, MD, Saibal Kar, MD
Cedars Sinai Heart Institute, Los Angeles, California, USA
Abstract
The MitraClip procedure is a safe and effective approach to reduction of mitral regurgitation (MR) with proven durability and clinical improvement. Procedural success is dependent on patient selection, understanding of mitral valve anatomy, particularly from an echocardiographic perspective, and attention to critical elements of the implantation such as trans septal puncture.
In the United States, the FDA has approved the MitraClip device for treatment of high risk patients with primary MR. The question of long term, sustained reduction of MR and persistent clinical improvement remains to be addressed with longer duration of follow up. Based on the impeccable safety profile of the procedure and demonstrated medium term clinical durability, future studies should be aimed at the evaluation of MitraClip for treatment of patients with severe MR deemed moderate, or indeed low risk, for surgery.
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Cite this article as: Sharma RP, Makar M, Kar S. An Overview of the Mitraclip Procedure: Indications, Procedural Characteristics, and Clinical Outcomes. Structural Heart Disease 2015;1(3):127-136. DOI: 10.12945/j.jshd.2015.018-14
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